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Dr. James Greenblatt joined me on The Doctor’s Farmacy and talked to me about the surprising positive effects that low doses of lithium can have on a lot of people struggling with mental health issues. Check out my full conversation with Dr. Greenblatt on your favorite podcast app.
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Lithium has a very narrow therapeutic window, and small changes in kidney function or medications can quickly push levels into the toxic range. One of the most important clinical pearls is remembering the medications and conditions that reduce lithium clearance. A simple way to remember the major culprits is SALT. S – Sodium depletion: dehydration, vomiting, diarrhea, or low sodium intake cause the kidneys to conserve sodium. Because lithium is handled like sodium in the proximal tubule, the kid
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