Promising developments in cardiovascular biomarker research. A new systematic review highlights GDF-15 (Growth Differentiation Factor 15) as an integrative biomarker linking obesity, subclinical atherosclerosis, and heart failure through shared pathophysiological pathways. ⭐ Key findings from this research: - GDF-15 demonstrates consistent associations with subclinical atherosclerotic markers including intima-media thickness, coronary artery calcium score, and atherosclerotic plaque burden - As
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