There are tests your doctor can perform to help confirm if you have acute hepatic porphyria (AHP)
There are tests your doctor can perform to help confirm if you have acute hepatic porphyria (AHP)
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Information about Porphyria | Alnylam
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Code HAVIC @medschoolbro = Mystery Discount Acute Intermittent Porphyria (AIP) 🧩 Dx: AIP — porphobilinogen deaminase deficiency ⚡ Triggers: CYP-inducers (barbs, anti-seizures), fasting, alcohol, infections 🖐 5 P’s: Painful abdomen, Port-wine urine (darkens on standing), Polyneuropathy/paresthesias & weakness, Psych changes, Precipitated by drugs 🧪 Labs: ↑ ALA & PBG in urine; normal LFT/lipase/CT 💉 Tx (first-line): Hemin glucose → downregulates ALA-synthase 🚫 Avoid CYP inducers; stop offendi
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Code HAVIC @medschoolbro = Mystery Discount Acute Intermittent Porphyria (AIP) 🧩 Dx: AIP — porphobilinogen deaminase deficiency ⚡ Triggers: CYP-inducers (barbs, anti-seizures), fasting, alcohol, infections 🖐 5 P’s: Painful abdomen, Port-wine urine (darkens on standing), Polyneuropathy/paresthesias & weakness, Psych changes, Precipitated by drugs 🧪 Labs: ↑ ALA & PBG in urine; normal LFT/lipase/CT 💉 Tx (first-line): Hemin glucose → downregulates ALA-synthase 🚫 Avoid CYP inducers; stop offendi
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Study Smarter with MedSchoolBro on Instagram: "Code HAVIC @medschoolbro = Mystery Discount Acute Intermittent Porphyria (AIP) 🧩 Dx: AIP — porphobilinogen deaminase deficiency ⚡ Triggers: CYP-inducers (barbs, anti-seizures), fasting, alcohol, infections 🖐 5 P’s: Painful abdomen, Port-wine urine (darkens on standing), Polyneuropathy/paresthesias & weakness, Psych changes, Precipitated by drugs 🧪 Labs: ↑ ALA & PBG in urine; normal LFT/lipase/CT 💉 Tx (first-line): Hemin + glucose → downregulates
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