What Is Subchondral Bone and Why Is It Important?
Jul 22, 2025 · Subchondral bone is the layer of bone located directly beneath the cartilage within a joint. This specialized bone is found in various joints throughout the body, including large weight-bearing …
Subchondral Sclerosis? Causes, Symptoms, and Treatment - WebMD
Sep 3, 2024 · “Subchondral bone” is bone that sits underneath cartilage in a joint. Subchondral bone is found in large joints like the knees and hips, as well as in small joints like those of the hands...
Subchondral bone microenvironment in osteoarthritis and pain
Mar 17, 2021 · Subchondral bone refers to the bony layer beneath the hyaline cartilage and cement line and can be divided into two parts anatomically, the subchondral bone plate (SBP) and subchondral …
Subchondral bone remodelling in osteoarthritis - PMC
Subchondral bone is the bedrock of a joint on which sits the articular cartilage.
What Is the Role of Subchondral Bone in Joint Health?
Nov 23, 2025 · The subchondral bone is the dense layer of bone tissue situated immediately beneath the articular cartilage within a joint. This structure, along with the cartilage it supports, forms the …
Subchondral Bone Definition - Anatomy and Physiology I Key Term
Subchondral bone provides structural support and shock absorption for the overlying articular cartilage in synovial joints. It is composed of dense, compact bone that is highly vascularized, allowing for …
Subchondral bone contribution to osteochondral health and injury
Jul 30, 2025 · This review focuses on recent translational research on the subchondral bone in both osteochondral health, injury, and OA, highlighting the need to preserve its integrity during cartilage …
What to Know About Subchondral Sclerosis and Sclerosis Bone Lesions
Sep 16, 2022 · Doctors can see subchondral sclerosis on a joint X-ray. The term “ sclerosis ” refers to a bone thickening that shows up denser on X-rays. In this case, it affects the subchondral bone. This is …
Subchondral bone in knee osteoarthritis: bystander or ... - Springer
Aug 30, 2023 · This narrative review aims to summarize the available and emerging imaging techniques used to evaluate knee OA-related subchondral bone changes and their potential role in clinical trials …
Subchondral bone: An emerging target for the treatment of articular ...
When dealing with the health status of the knee articular surface, the entire osteochondral unit has gained increasing attention, and in particular the subchondral bone, which plays a key role in the …