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Researchers describe a fundamental mechanism of antibiotic resistance. What happens in a bacterium that is resistant to the antibiotic fusidic acid? With a stop-motion movie at the atomic level, they ...
In an article published in Nature Communications, researchers from Uppsala Antibiotic Center, Uppsala University and ...
Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets.
New research by scientists at the University of Toronto and the Structural Genomics Consortium has deepened our understanding ...
Researchers found the PHGDH gene directly causes Alzheimer’s and discovered a drug-like molecule, NCT-503, that may help ...
Sarika Kondra and her co-author's TSR-based method represents a major advancement in protein structure analysis, integrating ...
Viruses are microscopic pathogens composed of genetic material housed within a protective protein shell ... in which phosphorylation of specific serine/threonine and tyrosine residues inhibits ...
Institute of Physical Biology, Heinrich-Heine-Universität Düsseldorf, Düsseldorf 40225, Germany Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum ...
A new study found that a gene recently recognized as a biomarker for Alzheimer’s disease is actually a cause of it, due to its previously unknown secondary function that triggers a pathway that ...
and proteins essential to normal biological function. The procedures presented in this paper allow structure determination at atomic resolution without ever removing the proteins from their membrane ...
To overcome these difficulties and visualize the architecture of a BLTP, we took a different approach and isolated the protein from the roundworm Caenorhabditis elegans. The structure showed that ...