The San Francisco 49ers were back in action on Sunday afternoon as they took on their NFC West rival, the Seattle Seahawks, ...

It may no longer be the 1990s, but a showdown between the San Francisco 49ers and Dallas Cowboys is always a treat. While neither team has lived up to expectations thus far, both teams are still ...

Pat O'Donnell will likely be called up from the practice squad to serve as the 49ers' punter for Week ... David Lombardi of The San Francisco Standard reports. Aiyuk sustained at least ACL and ...

Instead, it was the San Francisco 49ers who held on to win, 30-24, in prime time. The 49ers trailed the Cowboys 10-6 at halftime but turned the tide in their favor with three straight touchdown ...

The NFL has announced fines for two San Francisco 49ers players following their 27-24 victory over the Tampa Bay Buccaneers ...

The San Francisco 49ers have +1000 odds to win the Super Bowl, sixth-ranked in the league as of Nov. 13. The 49ers picked up a 23-20 win over the Tampa Bay Buccaneers in their last outing.

The 49ers have rewarded cornerback Deommodore Lenoir with a new ... Will he return on Sunday at San Francisco, four weeks after suffering the injury? “I don’t know yet,” Metcalf told reporters on ...

Join NBC Bay Area and Telemundo 48 on Dec. 1 for a 49ers-Bills watch party at Thrive City outside Chase Center in San ...

Inman: 10 things to catch my eye in 49ers’ escape from Tampa San Francisco 49ers | 49ers’ panicked fans get a dose of reality to go with nail-biting wins San Francisco 49ers | 49ers report ...

Tight end Noah Fant (groin), tight end Brady Russell (foot), and center Connor Williams (personal) have been ruled out for Sunday’s game against San Francisco. 49ers receiver Ricky Pearsall scored his ...

Check out the best plays from San Francisco 49ers defensive back Deommodore Lenoir's first four seasons in the NFL. San Francisco 49ers QB Brock Purdy zipped a touchdown dime to TE George Kittle ...

The San Francisco 49ers made a series of roster moves ahead of their Week 11 matchup against the Seattle Seahawks The San Francisco 49ers have signed P Pat O'Donnell to the team's practice squad.