DNA-labeled antibodies offer the advantage of simultaneous detection of multiple target molecules via orthogonal DNA barcode sequences. However, current methods for antibody-DNA conjugation typically ...

A novel AI-driven method helps scientists stay ahead of viral evolution by engineering synthetic spike proteins that ...

Life depends on genes being switched on and off at exactly the right time. Even the simplest living organisms do this, but usually over short distances across the DNA sequence, with the on/off switch ...

Effective mucosal immunity in the intestine involves a fine balance between tolerance of the microbiome, recognition and elimination of pathogens, and inflammatory tissue injury. The anti-inflammatory ...

Jumper expressed deep gratitude to his UChicago mentors, Profs. Tobin Sosnick and Karl Freed, fondly recalling the ...

Gene sequencing enabled researchers to identify the specific milk protein that triggered a patient ... 4 in cluster 5 as well as increased IFN-alpha and IFN-gamma response genes in clusters ...

Department of Organic and Inorganic Chemistry, University of the Basque Country UPV/EHU, 48940 Leioa, Spain BIOFISIKA, Basque Center for Biophysics CSIC-UPV/EHU, University of the Basque Country ...

The similarity is solely in the structure and not in the protein sequence.> Zhong said, “It really demanded modern AI to formulate the three-dimensional structure very precisely to make this discovery ...

UT researchers have developed the first viable alternative to a 75-year-old method for sequencing proteins. Image of amino acids, the building blocks of proteins. Scientists at The University of Texas ...

Meal sequencing is a relatively simple strategy. The idea behind it is that you should eat foods in a specific order — namely, having protein, healthy fats and fiber-rich, nonstarchy vegetables ...

They successfully reconstructed the sequence of molecular ... our insight into protein folding disorders and their consequences, and will be important even beyond Alpha-1 antitrypsin deficiency." ...