The standard eukaryotic cell cycle consists of four phases: G1, S, G2, and M phases. There are three phase transitions in a cell cycle: G1/S to initiate DNA synthesis, G2/M to enter mitosis, and ...

And instead of the neat phases of sequential gene expression found in normal multiciliated cell differentiation, the cell cycle-related genes expressed by these mutated cells melded into each other, ...

Other imaging-based methods for assessing the cell cycle status of individual cells include metabolic labeling procedures that probe cells transversing S-phase 5,6,7,8,9,10,11,12,13, staining ...

Fig 1. A diagram showing cell cycle progression and DNA repair. Image credit: Tocris Bioscience. DNA Replication. During S-phase, DNA replication takes place in five stages. They are: initiation ...

They captured them at different stages of maturity, hoping to glimpse the genetic instructions it takes to grow cilia and found a pattern that looked like the cell cycle. Previous studies had found ...

New ways to understand metabolism offer pathways for advances in human health and disease Chinese researchers have decoded the metabolic cycle of yeast using mathematical analysis, revealing striking ...

Jones et al. inhibited CDK1 activity in asynchronous cells (cells at different phases of the cell cycle) and found that this reduced the area of focal adhesions.Subsequent work by Lock et al ...

The classic view of the cell cycle was established by pioneering experiments in yeast and sea urchins by Hartwell, Nurse, Hunt, and others. 3 In principle, the cell cycle represents the molecular ...