Nearly 150 years ago, scientists began to imagine how information might flow through the brain based on the shapes of neurons ...

The software ReciPro makes various crystallographic calculations, visualizes a crystal structure, simulates a diffraction pattern and high-resolution TEM image, indexes diffraction spots, plots ...

Here, we report the cryo-electron microscopy (cryo-EM) structures of C3aR in three distinct conformational states: apo, intermediate, and fully active. We determined the structures of the ligand-free ...

Because mast cell disorders comprise a range of clonal and nonclonal mast cell conditions and might share some similar clinical symptoms, a comprehensive diagnostic approach is needed to establish an ...

Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an ...

Transmission electron microscopy (TEM) is well-known for performing in situ ... low electron dose, and proper cell viability verification methods. Despite being highly demanding, so-called “live-cell” ...

Scientists need sharp tools to peek into the tiny world of biology, and fluorescence microscopy has been a game-changer for studying cells. It’s taken cellularresearch ... blending it with other ...

Which sexy blonde nepo kid was seen leaving a famous sex toy shop in Hollywood? She was visiting The Pleasure Chest in Hollywood The bra you've been waiting for: Meet the range of cotton bras that ...

Next to their role in IgE-mediated allergic diseases and in promoting inflammation, mast cells also have antiinflammatory functions. They release pro- as well as antiinflammatory mediators, depending ...