Michael Wolff was at the "edge of a cliff" when he was diagnosed with a cancer that affects less than 300 patients a year in ...

In recent years, cell therapies have developed alongside chemotherapy and immunotherapy to become a new pillar in the treatment of patients with blood and lymph gland cancer. In solid tumors, such as ...

Cold' tumors are resistant to common immunotherapies. Researchers have uncovered a master regulator that can be manipulated to prevent tumor growth in mice.

The technology is genuinely useful for scientific discovery, but its applications are less dramatic than you might think.

Familial adenomatous polyposis (FAP) is a hereditary disease which, in addition to carrying a high risk of bowel cancer, also ...

In 2021, research led by Ryan Flynn, MD, PhD, and his mentor, Nobel laureate Carolyn Bertozzi, PhD, opened a new chapter in biology, characterizing a new kind of player on the cell surface: glycoRNAs.

The researchers analyzed gene and protein expression, along with lipid profiles, in the bone marrow of mice whose Elovl2 gene ...

A Ludwig Cancer Research study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive ...

Background: T-cell receptor (TCR) repertoires provide insights into tumor immunology, yet their variations across digestive system cancers are not well understood. Characterizing TCR differences ...

The GI Cancers Symposium revealed new therapies for specific cancer subsets and progress in chimeric antigen receptor T-cell therapies for solid tumors. The recent American Society of Clinical ...

4A,B). At the same time the percentage of undifferentiated spermatogonial stem cells in iDKO animals was unchanged, nor was the proportion of Leydig cells altered. Sertoli cells became the most ...