Panelists discuss how diagnosis and staging of anal cancer involves digital rectal examination, high-resolution anoscopy with biopsy, p16 testing, and pelvic MRI for accurate staging, while ...

A p16-positive test result suggests that the patient’s cancer may be due to any of the over 100 types of HPV.

#P16 histochemistry test to determine infection with any of > 100 types of HPV *Confirmatory PCR test for HPV16-positive specific infection Kevin Harrington, M.D., Ph.D. of The Institute of Cancer ...

The expansion of the use of HPV-specific testing on cytology specimens — over p16 alone or no testing at all — should help decrease the rate of nondiagnostic cervical lymph nodes by fine ...

Investigators in the multicenter trial enrolled patients with newly diagnosed HPV p16-positive oropharyngeal cancer, T1-T2N1M0 or T3N0-N1M0, and ≤10 pack-year history of smoking.

Double-tested patients revealed 46.5% (3,560 patients) were negative for both P16 and HPV and 44.3% (3,390) were positive for the protein and the virus. Of those with discordant test results, 3.8% ...

Patients with head and neck cancer who have equivocal results on routine p16 assay for HPV should be tested again with a test that measures HPV DNA, say researchers.

The second type of test looks for a protein called P16, which has been established as a commonly used biomarker for HPV. P16 is easier to use and so most people use it as the standard.

Tumors were tested for presence of HPV p16, and all serum samples were tested for eight HPV types associated with cancer. Men accounted for more than 80% of study participants.

In this prospective study, a pan-pathogen microarray was used to determine the virome of early stage, p16-positive OPSCC and neck metastasis treated with transoral robotic surgery and neck dissection.

P16 immunohistochemistry and in situ hybridization (ISH) for HPV-16, high-risk DNA, and/or E6/E7 RNA were performed. Age at diagnosis was compared by p16 and ISH tumor status.