Multiple types of HPV are associated with HSNCC, and those cases are commonly identified with a p16 histochemistry test and referred to as p16-positive.

Multiple types of HPV are associated with HSNCC, and those cases are commonly identified with a p16 histochemistry test and referred to as p16-positive.

HPV testing is not required for clinical management, so treatments are often administered on the basis of p16 status alone. However, the prognosis of p16/HPV discordant tumors is uncertain.

Investigators in the multicenter trial enrolled patients with newly diagnosed HPV p16-positive oropharyngeal cancer, T1-T2N1M0 or T3N0-N1M0, and ≤10 pack-year history of smoking.

There's a new way to screen for high-risk HPV, a viral infection that can lead to cervical cancer. This alternative method of collecting samples for cervical cancer screening doesn't require a ...

Abstract. African Americans exhibit lower survival rates from Human Papillomavirus (HPV)-induced squamous cell carcinomas in comparison to other population groups. While socioeconomic status and ...

Objective: Investigate HPV types in cervical specimens, their correlation with p16 expression in lesions, and diagnostic value for cervical lesions. Enhance clinical diagnosis reliability. Methods: ...

HPV status alone seems to be lacking prognostic relevance. In contrast, p16 status was confirmed as an independent prognostic factor. Thus, the expression of p16INK4a is associated with a ...

DNA HR HPV, mRNA (messenger ribonucleic acid) HPV and p16 tests should be considered for anal cancer screening, as their accuracy has been shown for cervical cancer.

Oropharyngeal cancer patients who have discordant p16 and HPV status have worse prognosis than patients who have p16+/HPV+ disease, a study suggests.