Tim-3, a molecule involved in immune regulation, hinders plaque removal in Alzheimer’s disease. Blocking it in microglia improved brain health in mice, making it a potential treatment target. Tim-3 is ...

Furthermore, many peripheral neural stem cells that migrate out of the neural tube can differentiate into mature neurons and, to a limited extent, glial cells during embryonic and postnatal ...

Lastly, the complex ganglia of the enteric nervous system harbour glial cells, the enteric glia, that are remarkably similar to astrocytes. Neuregulin 1 (NRG1) seems to have exceptionally numerous ...

Furthermore, many pNSCs that migrate out of the neural tube can differentiate into mature neurons and, to a limited extent, glial cells during embryonic and postnatal development. The discovery of ...

RPE = retinal pigmented epithelial cells, MGC= Müller glial cells, RPC= retinal progenitor cells, NPC= neurogenic progenitor cells. Trajectory analysis of WT and P23H SC-RNA seq data. A) Expression ...

The authors suggest this approach could also be combined with other cell replacement therapies. Research in Goldman's lab has shown that glial cells called astrocytes also play an important role ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

The goal is to have these cells then develop into neurons and glial cells, which support and protect neurons. In an announcement last week, the research team led by Keio University stem cell ...

This may be attributed to the decreased levels of tryptophan indole metabolites, the heightened activity of enteric glial cells (EGCs), and the inhibition of AHR/CPY1A1 signaling pathway. Forty-two ...