Currently, dozens of known substances in the immune system combine with complement proteins when activated. A total complement measurement checks the activity of the main complement components by ...

But the complement system is an oft-overlooked part of the immune system that could be exploited to create new therapies. It’s more than a decade since the first checkpoint inhibitor hit the ...

To establish whether the effects of C1q on synapse elimination are mediated by the classical complement cascade, the authors examined another component of the cascade, C3. The expression of C3 in ...

Intensive research over the past several years has revealed dysregulation of the complement system to be the main ... while preserving early complement components that are crucial for the ...