CTC are outnumbered by red blood cells and leukocytes in the blood ... these clinical samples is often required to obtain pure tumor populations that will allow accurate detection, measurement ...

Human circulating tumor DNA “was overall consistently shorter than the fragment length of normal cell-free DNA,” the authors wrote in their paper. The findings could help improve cancer diagnosis and ...

A McGill University-led research collaboration has achieved a breakthrough in understanding how cancer spreads. A clinical ...

Improved methods for circulating tumor cell capture and analysis can ensure reproducible biomarker and omics insights across different cancer types. Mouadh Barbirou, is a molecular biologist at the ...

“The discovery of cell-free, circulating tumor DNA (ctDNA) as a direct, albeit imperfect, measurement of tumor burden opens new possibilities for monitoring MRD and tailoring therapies accordingly.

Unlike traditional biopsies that require cutting or inserting a needle to remove a piece of the tumour, a liquid biopsy only ...

Circulating tumor cells comprise a heterogeneous group with biological properties often distinct from their primary tumor cell counterparts. Knowledge of the molecular architecture of CTCs is ...

"Clinical ultrasound, like the kind used for pregnancy scans, creates real-time images ... cancer cells." In addition to revealing cells, the team used ultrasound and microbubbles as probes ...

In prostate cancer, reliable markers of disease status are important for selecting and monitoring treatment. Two recent studies have shown that increased levels of circulating cells predict worse ...

Patients who were positive for cytomegalovirus had more immune cells circulating in their blood before they started ...

Comparison of circulating tumor cell numbers before and after treatment is predictive for overall survival in patients with metastatic castration-resistant prostate cancer; this comparison is more ...

Detection requires precision because most RNA circulating in the bloodstream originates from blood-forming cells rather than tumors. Rare tumor-derived RNA molecules are often masked by the ...