Further candidates, including inhibitors of acetyl-lysine readers (bromodomain-containing proteins ... proteins can block their interaction with acetylated histone residues and decrease the ...

Covalent selection identified lysine-targeting covalent inhibitors against phosphoglycerate mutase 1 (PGAM1), bromodomain (BRD) family proteins, and ubiquitin-conjugating enzyme E2 N (UBE2N).