This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

School of Chemical Engineering and Light Industry, Guangdong Provincial Key Laboratory of Plant Resources Biorefinery, Guangdong University of Technology, Guangzhou 510632, China ...

Acetylation of proteins, generally on lysine residues, via an acetyl-coenzyme A donor, can have functional consequences, as in proteins contained within chromatin and metabolic enzymes.