S5D) (35). In these molecules, lysine was alpha-N acetylated and C-amidated, so they more closely resemble the backbone of a protein rather than that of a standalone amino acid. The proposed binding ...

We conducted an immunoprecipitation (IP) targeting acetyl-lysine residues to enrich lysine-acetylated proteins, followed by immunoblotting for the Flag tag to specifically detect ACSS2 acetylation ...

Compared with cysteine-targeting strategies, lysine serves as an alternative covalent binding site that circumvents the limitation of cysteine scarcity in ligand-binding pockets and broadens the ...

The essential amino acid, Lysine, is vital for several bodily functions. It aids the body in generating collagen, soaking up calcium, and bolstering the immune system. While lysine is found in a ...

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Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cells change their metabolic profiles in ...

Ph.D. Program in Biochemistry, The Graduate Center of the City University of New York, New York, New York 10016, United States Department of Chemistry, College of Staten Island, The City University of ...

Previously, we reported that acetylated polyamines inform upon presence of PDAC. Here, we assessed to what extent cystic fluid polyamines predict risk of malignancy for patients with IPMN. Methods: ...

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Department of Hypertension and Endocrinology, Center for Hypertension and Metabolic Diseases, Daping Hospital, Army Medical University, Chongqing Institute of ...