Preclinical testing has suggested that AIR-001 increases functional AAT protein levels and could address the lung and liver manifestations of the disease.
The firm submitted data from the ALKOVE-1 trial, in which neladalkib shrunk tumors in 31 percent of patients and showed promising activity against CNS lesions.
In its third major acquisition in the past six weeks, Gilead is buying a company that will add NaPi2b- and 5T4-targeting agents to its portfolio.
The trial is evaluating how the disclosure of polygenic risk scores for cardiovascular disease affects patients' outcomes.
A study found that in about 10 percent of patients, WGS picked up on clinically actionable information other panels missed.
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