Charleston Southern visits the South Carolina Upstate Spartans after RJ Johnson scored 21 points in the Buccaneers' 69-61 loss to the UNC Asheville Bulldogs.

Scientists have discovered a potential new treatment for familial hypercholesterolemia, inspired by signs seen in the Mona ...

Wednesday is a big day for South Carolina Gov. Henry McMaster. Yes, he's giving his eighth State of the State address. And he ...

A bill that would give certain South Carolina families public dollars to send their kids to private schools is back up for ...

A U.S. Air Force pilot was reported to be safe after a single-seat F-35 fighter jet crashed Tuesday during a training ...

A Nigerian man was extradited to the U.S. after being accused of extorting a South Carolina teen who later died by suicide.

The South Carolina Department of Education faces a civil rights lawsuit challenging its restrictions on how race and sex are ...

It’s Senior Bowl week and that means the top college football graduates from across the country will compete with each other ...

South Carolina was unable to find any offensive rhythm to start. The Gamecocks turned it over six times in the first six ...

The U.S. Senate voted Monday to confirm hedge fund manager and South Carolina native Scott Bessent as the 79th Secretary of ...

The 4th Circuit U.S. Court of Appeals upheld Stephen Corey Bryant's death penalty in South Carolina who appealed the sentence ...

Zack Albert profiles the long and colorful history Bowman Gray's history, hot dogs and the home of the hot modifieds.