Scientists have identified a new CAF subset in HNSCC using tissue cytometry and spatial transcriptomics. In two-thirds of cases, head and neck squamous cell carcinomas (HNSCC) require treatment ...

Paracancerous and cancer tissues obtained from surgically resected DLBCLs were split and processed for scRNA-seq and spatial transcriptomics. (B) Single-cell expression of all cells from healthy ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to ...

Scientists have discovered, for the first time, how root cells respond to their complex soil environment, revealing that ...

Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

Their work generates extensive multi-modal datasets using contemporary technologies including single-cell RNA sequencing (scRNA-seq), spatial transcriptomics, and multiplex immunohistochemistry.

Together, these advancements deliver unmatched performance for high fidelity single-cell spatial transcriptomics, enabling deeper insights into intratumor heterogeneity, immune cell infiltration ...

The team used cutting-edge spatial and single-cell transcriptomics to compare rice roots grown in conventional gel-based media with those grown in heterogeneous natural soils and hard soils.

Their work is pioneering spatial transcriptomics using digital spatial profiling approaches to study different types of cancer including lung and head and neck. Fast forward to 2025: Kulasinghe is ...