and RNA methylation (m6A) collaboratively fine-tune gene activity. DNA methylation, mediated by the DNA methyltransferase (DNMT) family, has long been associated with transcriptional repression or ...

Recent work shows that m6A RNA methylation is an important regulatory mechanism during development. Here they show that the m6A RNA methylase subunit METTL14 plays a critical role in ...

The finding clarifies an important aspect of cell biology, and may have clinical implications, since this messenger RNA modification, known as m6A, is the target of an emerging class of cancer ...

A tiny chemical modification commonly found on messenger RNAs plays a surprisingly large role in how cells respond to stress, according to a study led by Weill Cornell Medicine investigators.

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation ... Drosophila m6A ...