~ Breakthrough Therapy designation based on clinical evidence from Phase I/II trials showing meaningful slowing of disease progression ~ ~ Additional regulatory update and guidance on the ...

(RTTNews) - uniQure N.V. (QURE), Thursday said U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy designation to AMT-130 for the treatment of Huntingtons disease, a rare ...

“Receiving Breakthrough Therapy designation underscores both the urgent need for effective treatments for Huntington’s disease and the encouraging interim data demonstrating that AMT-130 has ...

The number of people living in the area who have the gene that causes the condition has been accurately counted for the first time in 35 years in research by the University of Aberdeen ...

Brian Watt, with dog Winnie, says he tries to have a healthy lifestyle after his diagnosis in 2016 Northern Scotland has one of the highest rates of Huntington's disease in the world, according to ...

Research in a mouse model of Huntington’s disease has shown that the adult brain can generate new neurons that integrate into key motor circuits. Building on previous work, the new findings ...

One of the areas of the brain where these cells congregate is the ventricular zone, which is adjacent to the striatum, a region of the brain devastated by Huntington's disease. The idea that the ...

LSU is nearly finished with spring practice. The last few weeks offered a preview of what the offensive line might look like. Here's an updated depth chart prediction before LSU wraps up spring ...

The normal functions of peptides that aggregate in Alzheimer’s, Parkinson’s, and Huntington’s have been largely overlooked by scientists, but some argue that they are critical for understanding the ...

Brain Changes in Huntington's Disease Decades Before Diagnosis Will Guide Future Prevention Trials Jan. 17, 2025 — Subtle changes in the brain, detectable through advanced imaging, blood and ...

Huntington’s disease (HD) is an autosomal dominantly inherited neurodegenerative disorder caused by expanded CAG trinucleotide repeats (>36) in exon 1 of HTT gene that encodes huntingtin protein.