Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.

(A, B) Immunoblot analysis of liver tissues with m6A family and representative ... and potential fatality. N6-methyladenosine (m 6 A), a prevalent post-transcriptional mRNA modification ...

Cancer Res (2025) 85 (8_Supplement_1): 2755. N6-Methyladenosine (m6A) is the most prevalent internal modification of eukaryotic mRNAs and affects the regulation of its target transcripts in all ...

anticancer and N6-methyladenosine (m6A) RNA-modifying activity. Following ethics approval and site initiation in March 2025, the Miranda centre is now fully authorised to recruit patients.

N6-methyladenosine (m6A), the most abundant internal RNA modification in humans, regulates most aspects of RNA processing. Prostate cancer is characterized by widespread transcriptomic dysregulation; ...

We investigated and validated the combination between circZFR and YTH N6-methyladenosine RNA binding protein F3 (YTHDF3) protein via circRNA pulldown assay, mass spectrometry, and RNA ...

RNA modifications including N6-methyladenosine (m6A) play crucial roles in the post-transcriptional regulation of gene expression and have been implicated in cancer progression and liver disease. We ...

Recent studies suggest that methyltransferase-like 3 (METTL3), a critical RNA methyltransferase, may regulate the nucleotide-binding oligomerized structural domain-like receptor protein 3 (NLRP3) ...