After inferring sequences of the protein's ancestors, the team tested proteins which might have had a higher RNA methyltransferase activity. Among these candidates, the team found a variant that ...

In a major breakthrough for diabetes treatment, scientists have found a new way to regenerate insulin-producing cells. This ...

Another company looking to initiate clinical trials with an epigenetic-editor-based treatment for hepatitis is nChroma Bio.

Clinically-Inspired Herbal Detox Tea Formulated to Target Metabolism-Disrupting Enzymes, Reduce Bloating, and Support ...

This study provides valuable findings on the role of site-specific DNA methylation changes during spermatogenesis and their contribution to paternal epigenetic inheritance. The study proposes that ...

More information: Zhao-Jun Pan et al, HC-Pro inhibits HEN1 methyltransferase activity, leading to autophagic degradation of AGO1, Nature Communications (2025). DOI: 10.1038/s41467-025-56320-z ...

Our MTA-cooperative PRMT5 inhibitor, PH020, now named BAY 3713372, has demonstrated competitive selectivity for PRMT5 bound to MTA and activity ... (protein arginine methyltransferase 5) and ...

A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper explains how monogenic and polygenic factors converge on key growth ...

suppressing their activity. A mechanistic study on vascular calcification in chronic kidney disease suggests that m6A methyltransferase-3 restrains the crucial osteogenic gene Runx2 expression ...

MELBOURNE, Australia and INDIANAPOLIS, April 16, 2025 /PRNewswire/ -- Telix Pharmaceuticals Limited (ASX: TLX, NASDAQ: TLX, ...

Eight patients were included in the study with adaptive dosing of intravenous TLX101 up to administered activity of 4 GBq before ... [8] MGMT (O 6-methylguanine-DNA methyltransferase) is an enzyme ...