Mast cell activation syndrome, or disease (MCAS), is a condition that causes mast cells to release these substances too frequently, resulting in severe allergic reactions. After detecting an ...

POTS, and EDS, which nearly met the full diagnostic criteria for MCAS. Additional research that uses rigorous, validated criteria is called for to elucidate whether there is a link between mast cell ...

Mast cell mediators, histamine, tryptase and NGF, released upon activation can excite sensory nerves and promote their growth. Corticotropin-releasing hormone, sensory nerves and the number of ...

The following is a summary of “Prevalence of Mast Cell Activation Disorders and Hereditary Alpha Tryptasemia Amongst POTS and EDS Patients: A Systematic Review,” published in the April 2025 issue of ...

The Trump administration has pressed forwards with plans to unleash a wave of trillions in public spending cuts ...