Detection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamer
Contributed by Mark M. Davis, February 18, 2016 (sent for review June 5, 2015; reviewed by Marc K. Jenkins and Andrew J. McMichael) The recognition of foreign peptide-MHCs by T cells is a central ...
CD8 + T cells have a central role in immune control of HIV. However, the recent failure of a T-cell-based vaccine trial prompts an urgent refocus on what constitutes an effective CD8 + T-cell response ...
Viruses and their mammalian hosts have co-evolved for millions of years, resulting in intricate host–pathogen interactions. As a result viruses have evolved several mechanisms to 'hide' from the host ...
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