Involvement of gene in lentivirus infections of sheep, goats has been established Date: April 30, 2014 Source: Elhuyar Fundazioa Summary: The mechanism of the action of the small ruminant ...

In her Ph.D. thesis, Helena Crespo-Otano has studied the mechanism of the action of the small ruminant lentivirus, a type of virus in the same family as HIV and which infects sheep and goat ...

Lentiviral infection of mouse blastocysts allows specific transduction of the trophectoderm and its extra-embryonic derivatives.

Lentiviral vectors have emerged as promising tools for both gene therapy and immunotherapy purposes. They exhibit several advantages over other viral systems in that they are less immunogenic and ...

The β2 common integrin subunit CD18 is essential for leukocyte–endothelial adhesion and extravasation to inflamed or infected tissue. Damaging variants in ITGB2, which encodes CD18, cause ...

Lentiviruses, the viral group that includes HIV, are an undeniable scourge. The viruses set up chronic, slow-brewing infections in mammals, typically crippling a subset of immune cells essential ...

In cats, this virus is referred to as Feline Immunodeficiency Virus (FIV), which is similar to Acquired Immunodeficiency ...

Lentivirus genus represents a diverse, yet exceptionally cohesive group of retroviruses. Their influence on the health and general well-being of animals and humans alike has been enormous. Members ...

Viral vectors are indispensable tools for advancing gene therapy discovery and development. As researchers progress towards clinically relevant processes, scaling up production and clarification of ...

Lentiviral vector gene therapy combined with low-exposure, targeted busulfan conditioning in infants with newly diagnosed SCID-X1 had low-grade acute toxic effects and resulted in multilineage ...

In her Ph.D. thesis, Helena Crespo-Otano has studied the mechanism of the action of the small ruminant lentivirus, a type of virus in the same family as HIV and which infects sheep and goat species.