Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele ...

Clinical Impact of Somatic Genomic Variants of Oncogenes and Tumor Suppressor Genes in Previously Treated Advanced Non–Small Cell Lung Cancer The following represents disclosure information provided ...

Characterizing normal hematopoiesis is critical to determining how this process is disrupted, leading to AML. However, current reference maps for normal hematopoiesis are imprecise or based on small ...

Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating ...

Understanding the biological interface of age-related genetic changes and diseases of aging, such as cancer and cardiovascular disease, is important to develop preventative therapies for a growing ...

Clonal hematopoiesis of indeterminate potential (CHIP) is a condition where blood stem cells accumulate mutations over time, influenced by both aging and external environmental factors.

More than 25% of adults in North America have dietary copper intake below the estimated average requirement of 0.7 mg/d1 Copper plays key roles in hematopoiesis, iron metabolism, and maintenance of ...

It may also indicate a complication of leukemia known as extramedullary disease (EMD). EMD occurs when leukemia involves several organ systems, such as the skin, lymphatic system, nervous system ...

The tumour itself was a grade 1 hemangioblastoma, which was around 6cm x 3cm and caused secondary issues with Daniel's eyesight. Daniel had a follow-up MRI after an eye test because of the brain ...

Scientists at the Center for Genomic Regulation (CRG) have developed an AI-based tool to design thousands of sequences that regulate DNA. They have also synthesized these molecules, called enhancers, ...