This article was originally published with the title “ The Three-Dimensional Structure of an Enzyme Molecule ” in Scientific American Magazine Vol. 215 No. 5 (November 1966), p. 78 doi:10.1038 ...

Our team showed that when we prompt an AI model, called RFdiffusion, with the structure and amino acid sequence of an active ...

Thus, understanding the interplay between structure, dynamics and function of enzymes in solution is an important goal in modern biochemistry. Generations of students have been introduced to this ...

The active site of an enzyme has a unique three-dimensional structure that allows it to bind to a specific substrate, much like a lock and key. This specificity ensures that enzymes catalyze only the ...

This useful study presents computational analyses of over 5,000 predicted extant and ancestral nitrogenase structures. While the data and some analyses are solid, the study remains incomplete in ...

An enzyme's ability to remain catalytically active at lower temperatures is linked to the flexibility of its molecular structure. However, the precise molecular mechanisms behind this adaptation ...

the protein that makes up hair and nails Enzymes Catalyse biological reactions ATPase: catalyses the breakdown of ATP and Cellulose synthase: catalyses the formation of cellulose from glucose ...

Scientists have long struggled to target proteins that lack defined structure and are involved ... engineering proteases—enzymes that cut proteins at specific sites—to selectively degrade ...

Therefore, Asp 278, Asn 466 and Asn 467 may also have important roles in the catalysis by malic enzymes. Structure refinement of the ME-oxalate complex was carried out with the program X-PLOR 26 ...

An enzyme's ability to remain catalytically active at lower temperatures is linked to the flexibility of its molecular structure. However, the precise molecular mechanisms behind this adaptation ...