The trimeric, α-helical coiled-coil core of the HIV-1 ... mediated cell fusion. Figure 1: Stereo view of contacts near the N-terminus of the outer helix of gp41. Figure 2: A structure-based ...

In July 1 advanced online Nature Immunology, Lisa Matthias and colleagues at the University of New South Wales, Sydney, Australia, show that disulfide exchange in domain 2 of CD4 is required for entry ...

The researchers identified the structure of this machine, the mitochondrial pyruvate carrier (MPC), and 50 years since its discovery, have shown how it operates like the lock on a canal to transport ...

13, 2025 — A study shows that high-grade glioma tumor cells harboring DNA alterations ... in the laboratory that mimic the original structure and the molecular property of the parental tumor ...

As observed by researchers, the unique structure ... block the entry of antibiotics. The strong positive charge of lariocidin, on the other hand, enabled it to enter the bacterial cell directly ...

It can capture COVID-19 viruses for rapid detection and prevent infection by blocking viral entry into cells. This innovative ... movement and gripping. The DNA structure determines the finger ...

“Our portfolio already included four of those: SARS-CoV-2, HIV, Nipah and Zika ... That starting point includes knowledge about viral structure, cell entry and the parts of the virus that ...

NEW YORK – In cell and gene therapies, the genetic machinery is key to producing the proteins missing or dysregulated in a disease, but whether the therapeutic cassette reaches target cells and how ...

Benjamin K. Chen, MD, PhD, discussed the next steps after the results of his study in genetic tagging showed promise in ...

Benjamin Chen, MD, PhD, of the Icahn School of Medicine at Mount Sinai, discusses the implications of his new study involving ...

A mathematical modeling study coordinated by UMC Utrecht has shown that sustained HIV remission (without rebound) or HIV ...

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.