These interactions presumably also compensate for the loss of base and backbone ... influence ETS domain–DNA interactions. Position 69 just C-terminal to the α3 DNA recognition helix of the ...

NER unfolds in three distinct stages: recognition, verification and repair ... to fill in the gap left behind. Finally, the ...

Apurinic/apyrmidinic endonuclease 1 (APE1) plays a central role in DNA repair by cleaving the DNA backbone 5′ of AP ... the steps in BER may involve recognition of a product–enzyme complex ...

Combinations of these atoms form the sugar-phosphate backbone of the DNA -- the sides of the ladder, in other words. Other combinations of the atoms form the four bases: thymine (T), adenine (A ...