A new study in Cell reveals that lamina-associated domains (LADs) in early mouse embryos are shaped by dynamic epigenetic ...

NEW YORK - Our congratulations to Ludwig Oxford Member Yang Shi, who was recognized by the ARC Foundation for Cancer Research with the ...

Cancer remains a critical concern in global health due to its high prevalence and mortality rates. Despite significant ...

The study by Li et al. provides fundamental findings supported by convincing evidence that they defined cellular reprogramming of androgen receptor in neuroendocrine prostate cancer (NEPC). The ...

“Accurate detection of DNA methylation—particularly 5mC and 5hmC—on native ... detection in April 2022 and extended support to 6mA in December 2024 for Fiber-seq chromatin architecture studies. HK2 is ...

Researchers developed a cost-effective assay to be used with chemicals and potential carcinogens associated with reversible ...

This review highlights the critical role of epigenetic regulation in nuclear receptor function, shedding new light on its ...

These changes include methylation and acetylation, which influence chromatin structure and gene accessibility. 1 Chromatin remodeling: Changes in nucleosome positioning that significantly alter ...

Additional data presented will underscore the potential of GRAIL's ctDNA-based targeted methylation assay for quantifying abnormal promoter methylation, which is a known hallmark of cancer and has ...

NSD2 overexpression disrupts chromatin methylation promoting oncogenic gene expression. Despite advancements in MM treatments, the t(4;14) translocation remains a poor prognostic marker. Interestingly ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.