Catheter-based closure of the left atrial appendage (LAA) was found to be not noninferior to physician-directed best medical care for the primary composite endpoint of stroke, systemic embolism, major ...

Inflammation plays a central role in the pathogenesis of atherosclerosis and cardiovascular disease. 1 Atherosclerosis in particular is an inflammatory process that involves endothelial dysfunction, ...

The ACC is pleased to announce the recipients of its 2026 Distinguished Awards. This year's honorees represent an exceptional group of individuals whose past and ongoing efforts have made meaningful ...

Until about 15 years ago, most cardiologists were found in private practices, where the physicians – usually in groups – owned the practice and had privileges for hospital-based services at one or ...

A single subcutaneous injection of the investigational drug zilebesiran, when added to existing treatment with a standard antihypertensive medication, reduced systolic blood pressure (SBP) by between ...

Ninerafaxstat, a novel cardiac mitotrope that targets energy metabolism, is safe and effective in the treatment of nonobstructive hypertrophic cardiomyopathy (HCM), according to the Phase 2 ...

About 50% of U.S. adults will develop high BP during their lifetime. High BP is the most prevalent and modifiable risk factor for cardiovascular disease and all-cause mortality. The overarching BP ...

Long-term melatonin use for insomnia was associated with a higher hazard of heart failure (HF), an increase in HF hospitalizations and a doubling of all-cause mortality over five years, according to a ...

Compared with placebo, PCSK9 inhibition with evolocumab reduced the risk of first cardiovascular events among patients with atherosclerosis or diabetes and without a previous myocardial infarction or ...

Few things in a clinician's life generates more stress and disruption than an allegation of professional malpractice. The litigation process and the uncertainty it creates may cause a clinician to ...

Artificial intelligence (AI) has tremendous potential to transform cardiovascular care in several key areas, from discovery to practice, according to a JACC State-of-the-Art Review published June 24, ...

A significant prevalence of elevated blood pressure (BP) measurements was found among young athletes during community heart screenings, according to research presented during ACC's Care of the ...