The interplay between ion channels and T cell immunology has emerged as a pivotal area in both basic and translational research. Ion channels, particularly voltage‐gated potassium channels such as Kv1 ...
The study from St. Jude Children's Research Hospital presents a new understanding of how a VGIC, crucial for the communication of neurons and muscle cells, can become unresponsive. Scientists at St.
Much like a city, the body relies on electricity to power its functions. Electrical currents keep the heart beating on pace, relax and contract muscles, and flow from neuron to neuron. To modulate the ...
Mutated variants of a particular ion channel cause difficult-to-treat epilepsy. A study published in the journal Nature now shows that a commonly used anesthetic drug, propofol, can restore the ...
In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...
Electrical impedance tomography–extracellular voltage activation technique simplifies drug screening
The EIT–EVA PCB sensor setup used to evaluate the effects of drugs on hERG channels. The sensor measures changes in extracellular resistance as voltage-gated hERG channels are activated and inhibited, ...
More is not necessarily better, as was previously examined in an article about the pitfalls of high-throughput screening (GEN, March 15, 2006, pg. 24), not the least of which is the terabytes of ...
Instrument Seeks to Advance Ligand-Gated Aspect of Critically Important Field The first decade of the 21st century has delivered an extraordinary range of new technologies with relevance to ...
image: From left to right, Dr. Chia-Hsueh Lee and Dr. Hongtu Zhao of the Department of Structural Biology at St. Jude Children's Research Hospital. Dr. Lee and Dr. Zhao are co-authors of a new study ...
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