Scientists have revealed how the electrical patterns formed within an embryo initiate a cascade of molecular changes that culminate in the development of cartilage and bone. Prior studies have shown ...

Scientists now have a better picture of how voltage-gated sodium (Na v) channels interact with certain animal toxins, thanks to structures solved with cryo-electron microscopy. These channels are ...

The study from St. Jude Children's Research Hospital presents a new understanding of how a VGIC, crucial for the communication of neurons and muscle cells, can become unresponsive. Scientists at St.

A new study in the Journal of General Physiology (http://www.jgp.org) provides fresh insight into voltage-gated channels—transmembrane ion channels that play a ...

The process of expressing a wide variety of voltage-gated and ligand-gated ion channels enables nociceptors to transduce receptor potential into single action potentials or multiple action potentials.

In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...

Hangzhou Healzen Therapeutics Co. Ltd. has divulged potassium voltage-gated channel subfamily KQT member 2/3 (KCNQ2/3) activators reported to be useful for the treatment of epilepsy, among others.

The voltage-gated potassium (Kv) channel Kv1.5 mediates the ${\rm I}_{{\rm Kur}}$ repolarizing current in human atrial myocytes and regulates vascular tone in multiple peripheral vascular beds.

image: From left to right, Dr. Chia-Hsueh Lee and Dr. Hongtu Zhao of the Department of Structural Biology at St. Jude Children's Research Hospital. Dr. Lee and Dr. Zhao are co-authors of a new study ...