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Notch signaling and epithelial-to-mesenchymal transition (EMT). Transformed, recruited and differentially activated cells surrounding the tumor form the tumor microenvironment. These cells inhibit ...
Tumor cells undergoing epithelial–mesenchymal transition (EMT) can profoundly modulate their microenvironment via enhanced secretion of multiple soluble factors, including IL-8, IL-6 ...
Lunit (KRX:328130.KQ), a leading provider of AI-powered solutions for cancer diagnostics and therapeutics, today announced ...
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News-Medical.Net on MSNLipid metabolism as a driver of therapy resistance in triple negative breast cancerLipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype known as triple-negative breast cancer (TNBC).
Researchers at Children's Hospital of Philadelphia (CHOP) developed a longitudinal atlas of neuroblastoma, a common and ...
Studies to determine whether epigenetic reprogramming of EMT and/or the tumor microenvironment will improve response to standard-of-care chemotherapy and immunotherapy. View a listing of lab members ...
Lipid metabolism has emerged as a central player in the progression and therapy resistance of breast cancer, particularly the aggressive subtype ...
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Study identifies key cell subpopulation and associated gene signature in neuroblastomaThe starter cells also demonstrated partial epithelial-to-mesenchymal transition (EMT ... microenvironment, the researchers analyzed scRNA-seq data from non-malignant cells within the tumor ...
Thanks to the NIH, researchers like Andrew Ewald have advanced our understanding of what allows a cancer cell from one part of the body to successfully grow in another part ...
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