cell heterogeneity, tissue architecture, tissue development and more. Gene expression can vary wildly in different parts of a tissue, particularly in complex samples, such as a tumor biopsy. The ...

Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to ...

More recently, single-cell sequencing technologies have uncovered previously unappreciated levels of cancer and immune cell heterogeneity ... “With spatial transcriptomics we are able, for ...

Charlene earned her MSc and PhD in cell biology from ... of Calgary To assess tumoral heterogeneity, Bose and his team prepared slides from 12 OSCC tumor samples resected from 10 patients. They next ...

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Multi-modal data integration of single-nuclei RNA and ATAC sequencing with spatial transcriptomics, provides new molecular insights into gene regulatory networks driving cell state transitions in ...

Scientists have identified a new CAF subset in HNSCC using tissue cytometry and spatial transcriptomics ... between cancer-associated fibroblasts (CAF) and T cells. The team was required to ...

Their work is pioneering spatial transcriptomics ... is the subset of CD8+ T cells that is infiltrating? Are those cells exhausted? Are they moving away from the tumor? What are the distance ...