A recent study looked at the impact of stereotyped B-cell receptor immunoglobulins in patients with chronic lymphocytic leukemia (CLL). A recent study evaluating the impact of stereotyped B-cell ...
Chronic lymphocytic leukemia (CLL) is a chronic malignancy of B cells and the most frequent hematologic cancer, representing 30–40% of all adult leukemias. 1 It is characterized by considerable ...
The study of intraclonal diversification (ID) in immunoglobulin (IG) genes offers valuable insight into the role of ongoing interactions with antigen in lymphomagenesis. We recently showed that ID in ...
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