Poorly differentiated, spindle cell malignancies, on sun damaged skin frequently pose a diagnostic ... very rarely as spindle cell squamous cell carcinoma (SCSCC), leiomyosarcoma or angiosarcoma.

Those cancers begin in other types of tissue, such as: Basal cell carcinoma. This is the most common form of all cancers. It occurs in cells lining the deepest part of the skin's outer layer.