Effect of body position on ventricular CSF methotrexate concentration following intralumbar administration. Paclitaxel pharmacokinetics were studied in 55 courses of therapy in 30 patients. Paclitaxel ...
OBJECTIVE: To compare the pharmacokinetics of gentamicin in infants receiving high-frequency oscillatory ventilation (HFOV) with infants receiving conventional mechanical ventilation. DESIGN: A ...
To develop and evaluate a whole-body physiologically based pharmacokinetic (WB-PBPK) model of bisoprolol and to simulate its exposure and disposition in healthy adults and patients with renal function ...
Appropriate dosage determination for aminoglycosides helps to achieve desirable levels of drug in the blood, thereby reducing the probability of ototoxicity, nephrotoxicity, and treatment failure. The ...
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