Phenotypic effects of deletions depend on the size and location of deleted sequences on the genome. For instance, deletions that span a centromere result in an acentric chromosome that will most ...

Ideograms and partial karyotypes are shown. For the deletions, the arrows indicate a) the deletion of chromosome 15q11-13 associated with Prader-Willi and Angelman syndromes, and b) the deletion ...