The discovery of the Bcl-2 protein family, as well as p53 and its involvement ... for example between BCL-2 and BAX, have been shown to promote apoptosis. Perhaps the most advanced of these ...
Northern blot, RNase protection and western blot demonstrated the induction of p21, MDM-2 and Bax expression in PXN100, but not PXN65. This was consistent with the p53 status of these tumours.
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