After inferring sequences of the protein's ancestors, the team tested proteins which might have had a higher RNA methyltransferase activity. Among these candidates, the team found a variant that ...

Unlike animals, plants do not possess an adaptive immune system with antibodies or T cells to fight viral infections. Instead, they rely on the RNA silencing system, which serves as their innate ...

The WD40 protein WDR5 is a core subunit of the human MLL and SET1 (hCOMPASS) histone H3 Lys4 (H3K4) methyltransferase ... promoting complex assembly and activity. These findings suggest that ...

Single-cell imaging and mass spectrometry data reveal adenosine in the DNA of mammalian cells can be methylated by METTL3 to form N6-methyladenosine in response to DNA damage.