The crucial nature of the contacts between cytosine methyl groups and the protein is underscored by mutational analysis; mutation of residues contacting either methyl group results in a ...

In animal cells, DNA can be modified by methylation of cytosine residues in CpG dinucleotides, and the N-terminal tails of histone proteins are subject to a wide range of different modifications ...

3 Cytosine methylation occurs when a methyl group binds to the fifth ... Because of this difference, unmethylated cytosines in single-stranded DNA become uracil residues after exposure to sodium ...

Figure 1 | Proposed mechanism of DNA methylation and demethylation. A) Within the genome, the majority of CpG pairs are methylated by addition of –CH 3 to cytosine. B) DNA methylation involves ...