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How epigenetic modifications can influence the onset and progression of various diseasesThe role of histone modifications in atherosclerosis is particularly highlighted, with changes in histone acetylation and methylation found in atherosclerotic tissues.
The basic pattern of genomic DNA methylation is established at the time of embryo implantation through a wave of de novo methylation, but CpG islands are protected through a mechanism that ...
What is the histone code? Different chemical marks, such as acetylation, methylation, or phosphorylation, are made to numerous residues on the N-terminal tails of histone proteins. Some posit that ...
Researchers at the Institute of Higher Nervous Activity and Neurophysiology of the Russian Academy of Sciences have obtained important data on the effect of DNA methylation on long-term synaptic ...
Correspondence to Dr William M Brown, Department of Sport Science and Physical Activity, Faculty of Education and Sport, Institute of Sport and Physical Activity Research, University of Bedfordshire, ...
Histones not only keep DNA organized, but also help regulate gene expression. How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell ...
Epigenetics is a rapidly growing field of study that focuses on the heritable changes in gene expression that occur without alterations to the underlying DNA sequence. These changes are caused by ...
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