The researchers have already begun investigating this interaction in mast cell-mediated inflammatory diseases in humans, exploring whether this discovery could lead to new approaches to treating ...

Readers reply to an essay on overdiagnosis in medicine.

The disease course is highly variable ... 1 Pathogenesis of CSU: The Role of Mast Cells Understanding the role of mast cells is key to grasping the underlying mechanisms of CSU.

Systemic mastocytosis (SM) is a rare disease driven by the KIT D816V mutation in about 95 percent of cases. Uncontrolled proliferation and activation of mast cells result in chronic, severe and ...

Jasper is a clinical-stage biotechnology company focused on developing briquilimab as a therapeutic for chronic mast cell diseases. Briquilimab is a targeted aglycosylated monoclonal antibody that ...

Preclinical Work Advancing with Plans to Select a Next-Generation Oral Small Molecule PTH1R Agonist to Accelerate Toward the Clinic Later This ...

Reports Q4 revenue $212,000, consensus $150,000. “Our Native Complex Platform continues to produce a deep pipeline of oral small molecule ...