The opioid epidemic is devastating America. Overdoses have passed car crashes and gun violence to become the leading cause of death for Americans under 55. The epidemic has killed more people than HIV ...

Placebo effects, in which patients experience relief without therapeutic treatment, increasingly have been considered as ...

Drug overdoses remain one of the leading causes of death in the U.S. Researchers have designed a new type of vaccine that blocks the dangerous effects of oxycodone and fentanyl.

Globally, opioid overdose deaths are more common than you think. It is one of the most important public health concerns, ...

When people overdose on opioids, whether they wake up on their own or are revived by Narcan, many doctors assume they are fully recovered. This is a mistake because hypoxia (insufficient oxygen to the ...

The mid-1980s was the era of cocaine and marijuana, when “Just Say No” was the centerpiece of the war on drugs and the government’s efforts to stem drug use and addiction. Since then, prescription ...

Proposals to ban or regulate kratom, a plant-based substance sold in gas stations, convenience stores, and vape shops, are ...

The properties of the drug are what one doctors calls “a 'wish list' for what we would want in a safer opioid” that could ...

Can a better environment stop opioid relapse? Environmental enrichment lowers stress hormones and reduces fentanyl seeking in ...

A novel mu-opioid receptor agonist showed strong analgesia without respiratory depression, tolerance, or significant ...

How does the placebo effect work? A new study identifies the vlPAG brain region and endogenous opioid signaling as the keys to expectancy-driven pain relief.