This includes comparative (tumour cell versus normal cell) investigation of nuclear organization, DNA methylation, histone modification and the consequences of genetic mutations in genes encoding ...

The team turned to a precision nuclear run-on sequencing technique called PRO-cap ... Sen and her colleagues studied fragments containing cryptic sites and compared the levels of histone methylation, ...

This includes investigation of nuclear organization, DNA methylation, histone modification and RNA transcription. Epigenetic processes can result in intergenerational (heritable) effects as well ...