In patients with head and neck squamous cell carcinoma, high p16 antibody expression might serve as a marker for infection with high-risk human papillomavirus (HPV).

HPV and p16 status were favorable prognostic factors among patients with recurrent or metastatic squamous cell carcinoma of the head and neck, according to study results. Athanassios Argiris, MD ...

The influence of p16 or HPV status on OS, PFS and locoregional control served as the primary endpoints. The trial included 253 patients, of whom 72% (n = 182) had evaluable p16 data.

Univariate survival analysis revealed p16, HPV, cohort, alcohol and smoking as having a significant effect on cause-specific survival ().Twenty-five patients received no treatment and eight ...

Overall, diagnostic accuracy was statistically significantly higher for p16/Ki-67 compared with hr-HPV. Compared to HPV, immunostain triage could have generated approximately $46,000 savings in ...

Number needed to harm calculations estimated one excess cancer-related death for every 10 p16+/HPV– patients, compared with that expected with p16+/HPV+ patients. Conclusion NLP classified head and ...

The results of immunohistochemical staining for HPV and p16 and in situ hybridization for HPV are summarized in Table 2.HPV DNA and protein were not detected in any of the 42 cases of squamous ...

The expansion of the use of HPV-specific testing on cytology specimens — over p16 alone or no testing at all — should help decrease the rate of nondiagnostic cervical lymph nodes by fine ...

Article Title. Prognostic implications of p16 and HPV discordance in oropharyngeal cancer (HNCIG-EPIC-OPC): a multicentre, multinational, individual patient data analysis ...

Double-tested patients revealed 46.5% (3,560 patients) were negative for both P16 and HPV and 44.3% (3,390) were positive for the protein and the virus. Of those with discordant test results, 3.8% ...

Low EGFR and high p16 (or higher HPV titer) expression are markers of good response to organ-sparing therapy and outcome, whereas high EGFR expression, combined low p53/high Bcl-xL expression, female ...