A study led by Brazilian researchers has produced a detailed description of the morphology of the nerves in the liver and how they control production of glucose when the organism is under stress. This ...

Objective To compare the efficacy of exercise, metformin and their combination on glucose metabolism in individuals with abnormal glycaemic control. Design Systematic review and network meta-analysis.

Schematic diagram of the mechanism by which HYAL1-mediated HA degradation regulates mitochondrial O-GlcNAcylation in postprandial hepatocytes through the redistribution of the HA catabolism metabolite ...

Neurons in the ventromedial nucleus of the hypothalamus that express the cholecystokinin b receptor (VMH Cckbr neurons) appear to support glucose production during hypoglycemia without broadly ...

One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels. This is because in these insulin-resistant patients, glucose production by ...

During fasting or exercise, immune cells (red) migrate to the pancreas and stimulate glucagon-producing cells (orange) to regulate blood sugar, with cell nuclei shown in blue. “For decades, immunology ...

New research by scientists at the Champalimaud Foundation has revealed a surprising new role for the immune system. Their study in mice found that during periods of low energy— such as intermittent ...